Matsukawa K, Hashimoto T, Matsumoto T, Ihara R, Chihara T, Miura M, Wakabayashi T, Iwatsubo T: ALS-linked mutations in profilin 1 exacerbate degeneration in the retina of Drosophila melanogaster through increasing the cytoplasmic localization of TDP-43. J Biol Chem 291:23464-23476, 2016

Tominaga A, Cai T, Takagi-Niidome S, Iwatsubo T, Tomita T: Conformational changes in transmembrane domain 4 of presenilin 1 are associated with altered Abeta42 production. J Neurosci 36:1362-1372, 2016

Hayashi Y, Nishimune H, Hozumi K, Saga Y, Harada A, Yuzaki M, Iwatsubo T, Kopan R, Tomita T: A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep 6:23969, 2016

Taniguchi-Watanabe S, Arai T, Kametani F, Nonaka T, Masuda-Suzukake M, Tarutani A, Murayama S, Saito Y, Arima K, Yoshida M, Akiyama H, Robinson A, Mann DMA, Iwatsubo T, Hasegawa M: Biochemical classification of tauopathies by immunoblot, protein sequence and mass spectrometric analyses of sarkosyl-insoluble and trypsin-resistant tau. Acta Neuropathol 131:267-280, 2016

Ikari Y, Akamatsu G, Nishio T, Ishii K, Ito K, Iwatsubo T, Senda M: Phantom criteria for qualification of brain FDG and amyloid PET across different cameras EJNMMI Physics 3:23, 2016

Kuwahara T, Inoue K, D’Agati VD, Fujimoto T, Eguchi T, Saha S, Wolozin B, Iwatsubo T, Abeliovich A: LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. Sci Rep 6:29945, 2016

Kanatsu K, Hori Y, Takatori S, Watanabe T, Iwatsubo T, Tomita T: Partial loss of CALM function reduces A42 production and amyloid deposition in vivo. Hum Mol Genet pii: ddw239, 2016

Miyagawa T, Ebinuma I, Morohashi Y, Hori Y, Chang MY, Hattori H, Maehara T, Yokoshima S, Fukuyama T, Tsuji S, Iwatsubo T, Prendergast GC, Tomita T: BIN1 regulates BACE1 intracellular trafficking and amyloid-β production. Hum Mol Genet 25:2948-2958, 2016