Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T:Roles of collagen XXV and its putative receptors PTPσ/δ in intramuscular motor innervation and congenital cranial dysinnervation disorder. Cell Rep 29: 4362-4376, 2019
Tanaka Y, Yamada K, Satake K, Nishida I, Heuberger M, Kuwahara T, Iwatsubo T: Seeding activity-based detection uncovers the different release mechanisms of seed-competent tau versus inert tau via lysosomal exocytosis. Front Neurosci 13:1258, 2019
Wakabayashi T, Yamaguchi K, Matsui K, Sano T, Kubota T, Hashimoto T, Mano A, Yamada K, Matsuo Y, Kubota N, Kadowaki T, Iwatsubo T: Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease. Mol Neurodegener 14:15, 2019
Sato K, Mano T, Matsuda H, Senda M, Ihara R, Suzuki K, Arai H, Ishii K, Ito K, Ikeuchi T, Kuwano R, Toda T, Iwatsubo T, Iwata A: Visualizing modules of coordinated structural brain atrophy during the course of Alzheimer’s disease conversion by applying methodology from gene co-expression analysis. Neuroimage Clinical 24:101957, 2019
Goncalves TJM, Boutillon F, Lefebvre S, Goffin V, Chanoine C, Iwatsubo T, Wakabayashi T, Oury F, Armand AS: Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation. Sci Rep 9:5878, 2019
Eto M, Hashimoto T, Shimizu T, Iwatsubo T: Characterization of the unique in vitro effects of unsaturated fatty acids on the formation of amyloid beta fibrils. PLOS One 14:e0219465, 2019
Yagi T, Kanekiyo M, Ito J, Ihara R, Suzuki K, Iwata A, Iwatsubo T, Aoshima K: Identification of prognostic factors to predict cognitive decline of early Alzheimer’s disease patients in the Japanese Alzheimer’s Disease Neuroimaging Initiative study. Alzheimers Dementia: Translational Research & Clinical Interventions 5:364-373, 2019
Ishida T, Tokuda K, Hisaka A, Honma M, Iwatsubo T, Moritoyo T, Suzuki H, Alzheimer’s Disease Neuroimaging Initiative. Development of a novel method to estimate chronological changes in disease progression. Clin Pharmacol Therapeut 105: 436-447, 2019
Sato K, Mano T, Ihara R, Suzuki K, Tomita N, Arai H, Ishii K, Senda M, Ito K, Ikeuchi T, Kuwano R, Matsuda H, Iwatsubo T, Toda T, Iwata A: Lower serum calcium as a potential risk factor for mild cognitive impairment conversion to early Alzheimer’s disease in Japanese Alzheimer’s Disease Neuroimaging Initiative. J Alz Dis 68:777-788, 2019
Park S, Park S-K, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW: Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLOS Genetics 15:e1008308, 2019
Bannai T, Mano T, Chen X, Ohtomo G, Ohtomo R, Tsuchida T, Koshi-Mano K, Hashimoto T, Okazawa H, Iwatsubo T, Tsuji S, Toda T, Iwata A: Chronic cerebral hypoperfusion shifts the equilibrium of amyloid beta oligomers to aggregation-prone species with higher molecular weight. Sci Rep 9:2827, 2019