Iwatsubo T, Saido TC, Mann DMA, Lee VM-Y, Trojanowski JQ: Full-length amyloid-β (1-42(43)) as well as amino-terminally modified and truncated amyloid-β42(43) deposit in diffuse plaques. Am J Pathol 149:1823-1830, 1996

Saido TC, Yamao-Harigaya W, Iwatsubo T, Kawashima S: Amino- and carboxyl-terminal heterogeneity of β-amyloid peptides deposited in human brain. Neurosci Lett 215:173-176, 1996

Mann DMA, Iwatsubo T: Diffuse plaques in the cerebellum and corpus striatum in Down’s syndrome contain amyloid β protein (Aβ) only in the form of Aβ42. Neurodegeneration 5:115-120, 1996

Nakano I, Iwatsubo T, Otsuka N, Kamei M, Matsumura K, Mannen T: Some unusual astrocytic responses against ghost tangles in a long survival case of juvenile Alzheimer’s disease–An electron microscopic study– J Neurol Sci 136:41-46, 1996

Mann DMA, Iwatsubo T, Ihara Y, Cairns NJ, Lantos PL, Bogdanovic N, Lannfelt L, Winblad B, Maat-Schieman MLC, Rossor MN: Predominant deposition of amyloid β42(43) in plaques in cases of Alzheimer’s disease and hereditary cerebral haemorrhage associated with mutations in the APP gene. Am J Pathol 148:1257-1266, 1996

Yamatsuji T, Matsui T, Okamoto T, Komatsuzaki K, Takeda S, Fukumoto H, Iwatsubo T, Suzuki N, Asami-Odaka A, Ireland S, Kinane B, Giambarella U, Nishimoto I: G protein-mediated neuronal DNA fragmentation induced by familial Alzheimer’s disease-associated mutants of APP. Science 272:1349-1352, 1996

Maruyama K, Tomita T, Shinozaki K, Kume H, Asada H, Saido TC, Ishiura S, Iwatsubo T, Obata K: Familial Alzheimer’s disease-linked mutations at Val717 of amyloid precursor protein are specific for the increased secretion of Aβ42(43). Biochem Biophys Res Comm 227:730-735, 1996

Mann DMA, Iwatsubo T, Cairns NJ, Lantos PL, Nochlin D, Sumi SM, Bird TD, Poorkaj P, Hardy J, Hutton M, Prihar G, Crook R, Rossor MN, Haltia M: Amyloid β protein (Aβ) deposition in chromosome 14-linked Alzheimer’s disease: predominance of Aβ42(43). Ann Neurol 40:149-156, 1996

Fukumoto H, Asami-Odaka A, Suzuki N, Shimada H, Ihara Y, Iwatsubo T: Amyloid β protein (Aβ) deposition in normal aging has the same characteristics as that in Alzheimer’s disease: predominance of Aβ42(43) and association of Aβ40 with cored plaques. Am J Pathol 148:259-266, 1996

Kanemaru K, Iwatsubo T, Ihara Y: Comparable amyloid β protein (Aβ) 42(43) and Aβ40 deposition in the aged monkey brain. Neurosci Lett 214:196-198, 1996

Kume H, Maruyama K, Tomita T, Iwatsubo T, Saido TC, Obata K: Molecular cloning of a novel basic helix-loop-helix protein from rat brain. Biochem Biophys Res Comm 219:526-530, 1996

Mann DMA, Iwatsubo T, Snowden JS: Atypical amyloid (Aβ) deposition in the cerebellum in Alzheimer’s disease: an immunohistochemical study using end-specific Aβ monoclonal antibodies. Acta Neuropathol 91:647-653, 1996

Iwatsubo T, Yamaguchi H, Fujimuro M, Yokosawa H, Ihara Y, Trojanowski JQ, Lee VM-Y: Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease. Am J Pathol 148:1517-1529, 1996

Fukumoto H, Asami-Odaka A, Suzuki N, Iwatsubo T: Association of Aβ40-positive senile plaques with microglial cells in the brains of patients with Alzheimer’s disease and in non-demented aged individuals. Neurodegeneration 5:13-17, 1996

Mann DMA, Iwatsubo T, Ihara Y, Fukumoto H, Odaka A, Suzuki N: Microglial cells and amyloid β protein (Aβ) deposition; association with Aβ40 containing plaques. Acta Neuropathol 90:472-477, 1995

Saido TC, Iwatsubo T, Mann DMA, Ihara Y, Shimada H, Kawashima S: Dominant and differential deposition of distinct β-amyloid peptide species, AβN3(pE), in senile plaques. Neuron 14:457-466, 1995

Iwatsubo T, Mann DMA, Odaka A, Suzuki N, Ihara Y: Amyloid β protein (Aβ) deposition: Aβ42(43) precedes Aβ40 in Down syndrome. Ann Neurol 37:294-299, 1995

Mann DMA, Pickering-Brown S, Siddons MA, Iwatsubo T, Ihara Y, Odaka A, Suzuki N: The extent of amyloid deposition in brain in Down’s syndrome does not depend upon the apolipoprotein E genotype. Neurosci Lett 196:105-108, 1995