Information

全研究実績

2019

基礎
325

Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T:Roles of collagen XXV and its putative receptors PTPσ/δ in intramuscular motor innervation and congenital cranial dysinnervation disorder. Cell Rep 29: 4362-4376, 2019

基礎
324

Tanaka Y, Yamada K, Satake K, Nishida I, Heuberger M, Kuwahara T, Iwatsubo T: Seeding activity-based detection uncovers the different release mechanisms of seed-competent tau versus inert tau via lysosomal exocytosis. Front Neurosci 13:1258, 2019

基礎
319

Wakabayashi T, Yamaguchi K, Matsui K, Sano T, Kubota T, Hashimoto T, Mano A, Yamada K, Matsuo Y, Kubota N, Kadowaki T, Iwatsubo T: Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease. Mol Neurodegener 14:15, 2019

基礎
323

Sato K, Mano T, Matsuda H, Senda M, Ihara R, Suzuki K, Arai H, Ishii K, Ito K, Ikeuchi T, Kuwano R, Toda T, Iwatsubo T, Iwata A: Visualizing modules of coordinated structural brain atrophy during the course of Alzheimer’s disease conversion by applying methodology from gene co-expression analysis. Neuroimage Clinical 24:101957, 2019

基礎
318

Goncalves TJM, Boutillon F, Lefebvre S, Goffin V, Chanoine C, Iwatsubo T, Wakabayashi T, Oury F, Armand AS: Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation. Sci Rep 9:5878, 2019

基礎
320

Eto M, Hashimoto T, Shimizu T, Iwatsubo T: Characterization of the unique in vitro effects of unsaturated fatty acids on the formation of amyloid beta fibrils. PLOS One 14:e0219465, 2019

基礎
321

Yagi T, Kanekiyo M, Ito J, Ihara R, Suzuki K, Iwata A, Iwatsubo T, Aoshima K: Identification of prognostic factors to predict cognitive decline of early Alzheimer’s disease patients in the Japanese Alzheimer’s Disease Neuroimaging Initiative study. Alzheimers Dementia: Translational Research & Clinical Interventions 5:364-373, 2019

基礎
315

Ishida T, Tokuda K, Hisaka A, Honma M, Iwatsubo T, Moritoyo T, Suzuki H, Alzheimer’s Disease Neuroimaging Initiative. Development of a novel method to estimate chronological changes in disease progression. Clin Pharmacol Therapeut 105: 436-447, 2019

基礎
317

Sato K, Mano T, Ihara R, Suzuki K, Tomita N, Arai H, Ishii K, Senda M, Ito K, Ikeuchi T, Kuwano R, Matsuda H, Iwatsubo T, Toda T, Iwata A: Lower serum calcium as a potential risk factor for mild cognitive impairment conversion to early Alzheimer’s disease in Japanese Alzheimer’s Disease Neuroimaging Initiative. J Alz Dis 68:777-788, 2019

基礎
322

Park S, Park S-K, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW: Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLOS Genetics 15:e1008308, 2019

基礎
316

Bannai T, Mano T, Chen X, Ohtomo G, Ohtomo R, Tsuchida T, Koshi-Mano K, Hashimoto T, Okazawa H, Iwatsubo T, Tsuji S, Toda T, Iwata A: Chronic cerebral hypoperfusion shifts the equilibrium of amyloid beta oligomers to aggregation-prone species with higher molecular weight. Sci Rep 9:2827, 2019

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