Hashimoto T, Fujii D, Naka Y, Kashiwagi-Hakozaki M, Matsuo Y, Matsuura Y, Wakabayashi T, Iwatsubo T: Collagenous Alzheimer amyloid plaque component impacts on the compaction of amyloid-β plaques. Acta Neuropathol Comm 8:212, 2020

Kuwahara T, Funakawa K, Komori T, Sakurai M, Yoshii G, Eguchi T, Iwatsubo T: Roles of lysosomotropic agents on LRRK2 activation and Rab10 phosphorylation. Neurobiol Dis 145:105081, 2020

Sato K, Mano T, Suzuki K, Toda T, Iwatsubo T, Iwata A: Attempt to predict A/T/N-based Alzheimer’s disease cerebrospinal fluid biomarkers using a peripheral blood DNA methylation clock. J Alzheimers Dis Rep 4:287-296, 2020

Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Kawai K, Murakami M, Tanaka T, Goda W, Goto M, Yamamoto T, Hashimoto T, Yamada K, Shibata T, Misawa H, Mimura M, Tanaka KF, Miyakawa T, Iwatsubo T, Hata J-i, Niikura T, Yasui M: Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model. Acta Neuropathol Comm 8: 67, 2020

Suzuki K, Hirakawa A, Ihara R, Iwata A, Ishii K, Ikeuchi T, Sun C-K, Donohue M, Iwatsubo T: Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer’s disease. Alzheimers Dementia: Translational Research & Clinical Interventions 6:e12007, 2020

Okada Y, Kato T, Iwata K, Kimura Y, Nakamura A, Hattori H, Toyama H, Ishii K, Ishii K, Senda M, Ito K, Iwatsubo T: Evaluation of PiB visual interpretation with CSF Aβ and longitudinal SUVR in J-ADNI study. Ann Nucl Med 34: 108-118, 2020

Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T：Roles of collagen XXV and its putative receptors PTPσ/δ in intramuscular motor innervation and congenital cranial dysinnervation disorder. Cell Rep 29: 4362-4376, 2019

Tanaka Y, Yamada K, Satake K, Nishida I, Heuberger M, Kuwahara T, Iwatsubo T: Seeding activity-based detection uncovers the different release mechanisms of seed-competent tau versus inert tau via lysosomal exocytosis. Front Neurosci 13:1258, 2019

Sato K, Mano T, Matsuda H, Senda M, Ihara R, Suzuki K, Arai H, Ishii K, Ito K, Ikeuchi T, Kuwano R, Toda T, Iwatsubo T, Iwata A: Visualizing modules of coordinated structural brain atrophy during the course of Alzheimer’s disease conversion by applying methodology from gene co-expression analysis. Neuroimage Clinical 24:101957, 2019

Park S, Park S-K, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW: Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLOS Genetics 15:e1008308, 2019

Yagi T, Kanekiyo M, Ito J, Ihara R, Suzuki K, Iwata A, Iwatsubo T, Aoshima K: Identification of prognostic factors to predict cognitive decline of early Alzheimer’s disease patients in the Japanese Alzheimer’s Disease Neuroimaging Initiative study. Alzheimers Dementia: Translational Research & Clinical Interventions 5:364-373, 2019

Eto M, Hashimoto T, Shimizu T, Iwatsubo T: Characterization of the unique in vitro effects of unsaturated fatty acids on the formation of amyloid beta fibrils. PLOS One 14:e0219465, 2019

Wakabayashi T, Yamaguchi K, Matsui K, Sano T, Kubota T, Hashimoto T, Mano A, Yamada K, Matsuo Y, Kubota N, Kadowaki T, Iwatsubo T: Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer’s disease. Mol Neurodegener 14:15, 2019

Goncalves TJM, Boutillon F, Lefebvre S, Goffin V, Chanoine C, Iwatsubo T, Wakabayashi T, Oury F, Armand AS: Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation. Sci Rep 9:5878, 2019

Sato K, Mano T, Ihara R, Suzuki K, Tomita N, Arai H, Ishii K, Senda M, Ito K, Ikeuchi T, Kuwano R, Matsuda H, Iwatsubo T, Toda T, Iwata A: Lower serum calcium as a potential risk factor for mild cognitive impairment conversion to early Alzheimer’s disease in Japanese Alzheimer’s Disease Neuroimaging Initiative. J Alz Dis 68:777-788, 2019

Bannai T, Mano T, Chen X, Ohtomo G, Ohtomo R, Tsuchida T, Koshi-Mano K, Hashimoto T, Okazawa H, Iwatsubo T, Tsuji S, Toda T, Iwata A: Chronic cerebral hypoperfusion shifts the equilibrium of amyloid beta oligomers to aggregation-prone species with higher molecular weight. Sci Rep 9:2827, 2019

Ishida T, Tokuda K, Hisaka A, Honma M, Iwatsubo T, Moritoyo T, Suzuki H, Alzheimer’s Disease Neuroimaging Initiative. Development of a novel method to estimate chronological changes in disease progression. Clin Pharmacol Therapeut 105: 436-447, 2019